Cumulative publication list

[A1] Ultrasensitive fitness costs arise from membrane proteome displacement under protein overexpression

Müller, J., Gadjisade, N., Angermayer, S.A., Ansmann, G., Bollenbach, T., Cell Systems, in press, 26. Aug 2026, 10.1016/j.cels.2026.101709

[A3] Enzyme kinetics shapes the growth response of metabolic networks

Seeger, L., Pinheiro, F., Lässig, M., PLOS Computational Biology, 22(8), 19. Aug 2026, 10.1371/journal.pcbi.1014642

[A1] Function-specific epistasis shapes evolutionary trajectories towards antibiotic resistance

Petrungaro, G., Fink, T., Fernando, B., Ansmann, G., Bollenbach T., Nature Communications, 17, 7564, 28. Jul 2026, 10.1038/s41467-026-76025-1

[A2] [A1] [A5] Contributions of intra- and extracellular antibiotic degradation to collective β-lactam survival

Gross, R., Mungan, M., Das, S.G., Yüksel, M., Maier, B., Bollenbach, T., de Visser, J.A.G.M., Krug, J., Proc. Natl. Acad. Sci. U.S.A., 123 (29) e2526410123, 15. Jul 2026, 10.1073/pnas.2526410123

[A1] [A7] Predicting antimicrobial resistance for precision medicine

Fink, T., Rybniker, J., Bollenbach, T., Cell Host & Microbe, 34(7), 1186–1201, 08. Jul 2026, 10.1016/j.chom.2026.05.031

[A4] The Fate of Horizontally Acquired Genes: Rapid Initial Turnover Followed by Long-Term Persistence

Mishra, S., Weit, K., Lercher, M. J., Molecular Biology and Evolution, 43(7), 07. Jul 2026, 10.1093/molbev/msag146

[A3] [B2] Adaptive Ratchets and the Evolution of Molecular Complexity

Röschinger, T., Moran-Tovar, R., Pompei, S., & Lässig, M., PRX Life, 4, 023004, 09. Apr 2026, 10.1103/bhf2-3v22

[B4] AEGIS: Individual-based modeling of life history evolution

Bagic, M., Šajina, A., Bradshaw, W. J., & Valenzano, D. R, PLOS Computational Biology, 22(3), e1014109, 26. Mar 2026, 10.1371/journal.pcbi.1014109

[C1] A feedback loop between cell proliferation and ROS regulates ferroptosis sensitivity

Seidel E, Itak EY, Müller F, Yapici FI, Brägelmann J, Berg J & von Karstedt S, Front. Cell Dev. Biol., 14:1756238, 25. Mar 2026, 10.3389/fcell.2026.1756238

[B4] Spontaneous aging-associated inflammation and genome instability in the immune system of turquoise killifish

Morabito, G., Dönertas, H. M., Sperti, L., Seidel, J., Poursadegh Zonouzi, A., Poeschla, M., & Valenzano, D. R. , Nature Aging, 6(3), 20. Mar 2026, 0.1038/s43587-026-01086-2

[B1] [B2] Pre-existing neutralizing antibodies against cattle-transmitted influenza A virus H5N1 are detectable in unexposed individuals

Daniel, K., Ullrich, L., Ruchnewitz, D., Meijers, M., ..., Lässig M., Kreer C., Klein, F., Immunity, 59(2), 10. Feb 2026, 10.1016/j.immuni.2025.12.013

[C1] Branch length statistics in phylogenetic trees under constant-rate birth-death dynamics

Dieselhorst, T., & Berg, J, Journal of Theoretical Biology, 621, 08. Jan 2026, 10.1016/j.jtbi.2025.112355

[C1] Phylodynamics of Somatic Evolution: A Likelihood-Based Approach for Cellular Reproduction

Dieselhorst, T., & Berg, J, Molecular Biology and Evolution, 43(2), 06. Jan 2026, 10.1093/molbev/msag002

[B1] Profiling of HIV-1 elite neutralizer cohort reveals a CD4bs bnAb for HIV-1 prevention and therapy

Gieselmann, L., DeLaitsch, A.T., ..., Klein F, Nature Immunology, 26, 06. Oct 2025, 10.1038/s41590-025-02286-5

[C4] Single-cell analysis of Barrett’s esophagus and carcinoma reveals cell types conferring risk via genetic predisposition

enzel, M. C., Dasmeh, P., Plum, P. S., Giel, ..., & Hillmer, A. M, Cell Genomics, 5(10), 08. Sep 2025, 10.1016/j.xgen.2025.100980

[C3] Deep learning-based interpretable prediction of recurrence of diffuse large B-cell lymphoma

Naji, H., Hahn, P., Pisula, J. I., Ugliano, S., Simon, A., Büttner, R., & Bozek, K, BJC Reports, 3(1), 20. May 2025, 10.1038/s44276-025-00147-0

[C1] Deep transfer learning approach for automated cell death classification reveals novel ferroptosis-inducing agents in subsets of B-ALL

Stachura, P., Lu, Z., Kronberg, R. M., Xu, H. C., Liu, W., Tu, J.-W., Schaal, K., Kameri, E., Picard, D., Von Karstedt, S., Fischer, U., Bhatia, S., Lang, P. A., Borkhardt, A., & Pandyra, A. A, Cell Death & Disease, 16(1), 18. May 2025, 10.1038/s41419-025-07704-y

[A4] DeepMolecules: a web server for predicting enzyme and transporter-small molecule interactions

Kroll, A., Rousset, Y., Spitzlei, T., and Lercher, M. J., Nucleic Acids Research, 29. Apr 2025, 10.1093/nar/gkaf343

[A2] Epistasis-mediated compensatory evolution in a fitness landscape with adaptational tradeoffs

Das, S. G., Mungan, M., & Krug, J, Proceedings of the National Academy of Sciences, 122(15), 11. Apr 2025, 10.1073/pnas.2422520122

[A4] Most bacterial gene families are biased toward specific chromosomal positions

Hu, X.-P., Brahmantio, B., Bartoszek, K., & Lercher, M. J, Science, 388(6743), 10. Apr 2025, 10.1126/science.adm9928

[A1] Extreme diversity of phage amplification rates and phage–antibiotic interactions revealed by PHORCE

Mulla, Y., Müller, J., Trimcev, D., & Bollenbach, T, PLOS Biology, 23(4), 08. Apr 2025, 10.1371/journal.pbio.3003065

[A2] Graph-structured populations elucidate the role of deleterious mutations in long-term evolution

Sharma, N., Das, S. G., Krug, J, Nature Communications, 16(1), 10. Mar 2025, 10.1038/s41467-025-57552-9

[C2] Analysis of Limited Proteolysis-Coupled Mass Spectrometry Data

Nagel, L., Grossbach, J., Cappelletti, V., Dörig, C., Picotti, P., & Beyer, A., Molecular & Cellular Proteomics, 24(4), 100934, 07. Mar 2025, 10.1016/j.mcpro.2025.100934

[B2] Concepts and Methods for Predicting Viral Evolution. In Y. Yamauchi & M. J. Amorim (Eds.)

Meijers, M., Ruchnewitz, D., Eberhardt, J., Karmakar, M., Łuksza, M., & Lässig, M, Influenza Virus, 01. Feb 2025, 10.1007/978-1-0716-4326-6_14

[A5] Pilin antigenic variants impact gonococcal lifestyle and antibiotic tolerance by modulating interbacterial forces

Wielert, I., Kraus-Römer, S., Volkmann, T. E., Craig, L., Higgins, P. G., & Maier, B, PLOS Biology, 23(1), 30. Jan 2025, 10.1371/journal.pbio.3003022

[A1] Trace elements increase replicability of microbial growth

Shimoga Nadig, A., Gross, R., Bollenbach, T., & Ansmann, G, Open Biology, 15(1), 29. Jan 2025, 10.1098/rsob.240301

[C1] Ferroptosis triggers mitochondrial fragmentation via Drp1 activation

Pedrera, L., Prieto Clemente, L., Dahlhaus, A., Lotfipour Nasudivar, S., Tishina, S., Olmo González, D., Stroh, J., Yapici, F. I., Singh, R. P., Grotehans, N., Langer, T., García-Sáez, A. J., & Von Karstedt, S, Cell Death & Disease, 16(1), 25. Jan 2025, 10.1038/s41419-024-07312-2

[C1] High-density sampling reveals volume growth in human tumours

Angaji, A., Owusu, M., Velling, C., Dick, N., Weghorn, D., & Berg, J, eLife, 13, 26. Nov 2024, 10.7554/eLife.95338.3

[A4] SPOT: A machine learning model that predicts specific substrates for transport proteins

Kroll, A., Niebuhr, N., Butler, G., & Lercher, M. J, PLOS Biology, 22(9), 26. Sep 2024, 10.1371/journal.pbio.3002807

[A3] [C5] Energy landscapes of peptide-MHC binding

Collesano, L., Łuksza, M., & Lässig, M, PLOS Computational Biology, 20(9), 03. Sep 2024, 10.1371/journal.pcbi.1012380

[A4] DLKcat cannot predict meaningful k cat values for mutants and unfamiliar enzymes

Kroll, A., and Lercher, M. J., Biology Methods and Protocols, Volume 9, Issue 1, 24. Aug 2024, 10.1093/biomethods/bpae061

[B2] Nonequilibrium Antigen Recognition during Infections and Vaccinations

Morán-Tovar, R., & Lässig, M, Physical Review X, 14(3), 14. Aug 2024, 10.1103/PhysRevX.14.031026

[B5] Combining mutation and recombination statistics to infer clonal families in antibody repertoires

Spisak, N., Athènes, G., Dupic, T., Mora, T., & Walczak, A. M, eLife, 13, 09. Aug 2024, 10.7554/eLife.86181

[C4] Integrative genomic analyses of European intrahepatic cholangiocarcinoma: Novel ROS1 fusion gene and PBX1 as prognostic marker

Plum, P. S., Hess, T., Bertrand, D., Morgenstern, I., Velazquez Camacho, O., Jonas, C., Alidousty, C., Wagner, B., Roessler, S., Albrecht, T., Becker, J., Richartz, V., Holz, B., Hoppe, S., Poh, H. M., Chia, B. K. H., Chan, C. X., Pathiraja, T., Teo, A. S., … Hillmer, A. M., ROS1 fusion gene and PBX1 as prognostic marker, Clinical and Translational Medicine, 14(6), 14. Jun 2024, 10.1002/ctm2.1723

[A4] A multimodal Transformer Network for protein-small molecule interactions enhances predictions of kinase inhibition and enzyme-substrate relationships

Kroll, A., Ranjan, S., & Lercher, M. J, PLOS Computational Biology, 20(5), 20. May 2024, 10.1371/journal.pcbi.1012100

[B1] SARS-CoV-2 Test-to-Stay in Daycare

Dewald, F., Steger, G., Fish, I., Torre-Lage, I., Hellriegel, C., Milz, E., Kolb-Bastigkeit, A., Heger, E., Fries, M., Buess, M., Marizy, N., Michaelis, B., Suárez, I., Rubio Quintanares, G. H., Pirkl, M., Aigner, A., Oberste, M., Hellmich, M., Wong, A., … Klein, F, Pediatrics, 153(5), 10. Apr 2024, 10.1542/peds.2023-064668

[A2] Evolutionary accessibility of random and structured fitness landscapes

Krug, J., & Oros, D, Journal of Statistical Mechanics: Theory and Experiment, 2024(3), 03. Apr 2024, 10.1088/1742-5468/ad3197

[A1] Invade to evade: E. coli’s gutsy survival strategies

Mulla, Y., & Bollenbach, T, Cell Host & Microbe, 32(3), 12. Mar 2024, 10.1016/j.chom.2024.02.006

[B4] Immune aging in annual killifish

Morabito, G., Ryabova, A., & Valenzano, D. R, Immunity & Ageing, 21(1), 08. Mar 2024, 10.1186/s12979-024-00418-3

[C3] HoLy-Net: Segmentation of histological images of diffuse large B-cell lymphoma

Naji, H., Sancere, L., Simon, A., Büttner, R., Eich, M.-L., Lohneis, P., & Bozek, K, Computers in Biology and Medicine, 170, 11. Jan 2024, 10.1016/j.compbiomed.2024.107978

[B1] Somatic hypermutation introduces bystander mutations that prepare SARS-CoV-2 antibodies for emerging variants

Korenkov M., Zehner M., Cohen-Dvashi H., Borenstein-Katz A., Kottege L., Janicki H., Vanshylla K., Weber T., Gruell H., Koch M., Diskin R., Kreer C., Klein F., Cell Immunity 1074-7613, 29. Nov 2023, 10.1016/j.immuni.2023.11.004

[B1] Enhanced SARS-CoV-2 humoral immunity following breakthrough infection builds upon the preexisting memory B cell pool

Weber T., Dähling S., Rose S., Affeldt P., Vanshylla K., Ullrich L., Gieselmann L., Teipel F., Gruell H., Di Cristanziano V., Kim D.S., Georgiou G., Koch M., Kreer C., Klein F., Sci. Immunol.8, eadk5845, 17. Nov 2023, 10.1126/sciimmunol.adk5845

[A5] Genome-wide transformation reveals extensive exchange across closely related Bacillus species

Förster M., Rathman I., Yüksel M., Power J., Maier B., Nucleic Acids Reasearch, 16. Nov 2023, 10.1093/nar/gkad1074

[B1] Single-cell analysis of memory B cells from top neutralizers reveals multiple sites of vulnerability within HCMV Trimer and Pentamer

Zehner, M., Alt, M., Ashurov, A., Goldsmith, J. A., Spies, R., Weiler, N., Lerma, J., Gieselmann, L., Stöhr, D., Gruell, H., Schultz, E. P., Kreer, C., Schlachter, L., Janicki, H., Laib Sampaio, K., Stegmann, C., Nemetchek, M. D., Dähling, S., Ullrich, L., … Klein, F, Immunity, 56(11), 14. Nov 2023, 10.1016/j.immuni.2023.10.009

[B1] Dynamics and durability of HIV-1 neutralization are determined by viral replication

Schommers, P., Kim, D. S., Schlotz, M., Kreer, C., Eggeling, R., Hake, A., Stecher, M., Park, J., Radford, C. E., Dingens, A. S., Ercanoglu, M. S., Gruell, H., Odidika, S., Dahlhaus, M., Gieselmann, L., Ahmadov, E., Lawong, R. Y., Heger, E., Knops, E., … Klein, F, Nature Medicine, 29(11), 13. Nov 2023, 10.1038/s41591-023-02582-3

[B1] [B5] Probabilities of developing HIV-1 bNAb sequence features in uninfected and chronically infected individuals

Kreer C., Lupo C, Ercanoglu M.S., Gieselmann L., Spisak N., Grossbach J., Schlotz M., Schommers P., Gruell H., Dold L., Beyer A., Nourmohammad A., Mora T., Walczak A.M., Klein F., Nat Commun, 14, 06. Nov 2023, 10.1038/s41467-023-42906-y

[B1] Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa

Simonis, A., Kreer, C., Albus, A., Rox, K., Yuan, B., Holzmann, D., Wilms, J. A., Zuber, S., Kottege, L., Winter, S., Meyer, M., Schmitt, K., Gruell, H., Theobald, S. J., Hellmann, A.-M., Meyer, C., Ercanoglu, M. S., Cramer, N., Munder, A., … Klein, F., Rybniker, J, Cell, 186(23), 01. Nov 2023, 10.1016/j.cell.2023.10.002

[B5] Evolutionary stability of antigenically escaping viruses

Chardès, V., Mazzolini, A., Mora, T., & Walczak, A. M, Proceedings of the National Academy of Sciences, 120(44), 23. Oct 2023, 10.1073/pnas.2307712120

[B2] Population immunity predicts evolutionary trajectories of SARS-CoV-2

Meijers M., Ruchnewitz D., Eberhardt J., Łuksza M., Lässig M., Cell, 23. Oct 2023, 10.1016/j.cell.2023.09.022

[A4] Proteome efficiency of metabolic pathways in Escherichia coli increases along the nutrient flow

Hu, X.-P., Schroeder, S., & Lercher, M. J., Escherichia coli increases along the nutrient flow, mSystems, 8(5), 05. Oct 2023, 10.1128/msystems.00760-23

[C2] Predicting the next move: Tracking the complexity of lung cancer evolution and metastasis

Lorenz, C., Hillmer, A. M., & Brägelmann, J, Signal Transduction and Targeted Therapy, 8(1), 09. Aug 2023, 10.1038/s41392-023-01567-5

[C1] Characterizing Evolutionary Dynamics Reveals Strategies to Exhaust the Spectrum of Subclonal Resistance in EGFR-Mutant Lung Cancer

Müller, N., Lorenz, C., Ostendorp, J., Heisel, F. S., Friese, U. P., Cartolano, M., Plenker, D., Tumbrink, H., Heimsoeth, A., Baedeker, P., Weiss, J., Ortiz-Cuaran, S., Büttner, R., Peifer, M., Thomas, R. K., Sos, M. L., Berg, J., & Brägelmann, J, Cancer Research, 83(15), 01. Aug 2023, 10.1158/0008-5472.CAN-22-2605

[C2] Genetic effects on molecular network states explain complex traits

Weith, M., Großbach, J., Clement-Ziza, M., Gillet, L., Rodríguez-López, M., Marguerat, S., Workman, C. T., Picotti, P., Bähler, J., Aebersold, R., & Beyer, A, Molecular Systems Biology, 19(8), 24. Jul 2023, 10.15252/msb.202211493

[A4] Turnover number predictions for kinetically uncharacterized enzymes using machine and deep learning

Kroll, A., Rousset, Y., Hu, X.-P., Liebrand, N. A., & Lercher, M. J, Nature Communications, 14(1), 12. Jul 2023, 10.1038/s41467-023-39840-4

[B2] [B3] Steering and controlling evolution — from bioengineering to fighting pathogens

Lässig M., Mustonen V., Nourmohammad A., Nat Rev Genet, 03. Jul 2023, 10.1038/s41576-023-00623-8

[B4] Dietary restriction mitigates the age-associated decline in mouse B cell receptor repertoire diversity

Monzó, C., Gkioni, L., Beyer, A., Valenzano, D. R., Grönke, S., & Partridge, L, Cell Reports, 42(7), 28. Jun 2023, 10.1016/j.celrep.2023.112722

[A4] Mathematical properties of optimal fluxes in cellular reaction networks at balanced growth

Dourado, H., Liebermeister, W., Ebenhöh, O., and Lercher, M. J., PLOS Comput Biology, 06. Jun 2023, 10.1371/journal.pcbi.1011156

[A1] Quantitative approaches to study phenotypic effects of large-scale genetic perturbations

Müller, J., & Bollenbach, T, Current Opinion in Microbiology, 74, 03. Jun 2023, 10.1016/j.mib.2023.102333

[A4] A general model to predict small molecule substrates of enzymes based on machine and deep learning

Kroll, A., Ranjan, S., Engqvist, M. K. M., & Lercher, M. J, Nature Communications, 14(1), 15. May 2023, 10.1038/s41467-023-38347-2

[C4] Why loss of Y? A pan-cancer genome analysis of tumors with loss of Y chromosome

Müller, P., Velazquez Camacho, O., Yazbeck, A. M., Wölwer, C., Zhai, W., Schumacher, J., Heider, D., Buettner, R., Quaas, A., & Hillmer, A. M, Computational and Structural Biotechnology Journal, 21, 15. Feb 2023, 10.1016/j.csbj.2023.02.024

[A2] [A3] [B2] Towards evolutionary predictions: Current promises and challenges

Wortel, M.T.,...,Krug, J.,...,Lässig, M.,...,de Visser, J. A. G. M.,...,Pennings, P. S., Evolutionary Applications, 16(1), 3–21, 09. Dec 2022, 10.1111/eva.13513

[C1] Extrinsic cell death pathway plasticity: A driver of clonal evolution in cancer

Seidel, E., & Von Karstedt, S, Cell Death Discovery, 8(1), 26. Nov 2022, 10.1038/s41420-022-01251-7

[A2] Conflicting effects of recombination on the evolvability and robustness in neutrally evolving populations

Klug, A., & Krug, J, PLOS Computational Biology, 18(11), 21. Nov 2022, 10.1371/journal.pcbi.1010710

[C2] Global, in situ analysis of the structural proteome in individuals with Parkinson's disease to identify a new class of biomarker

Mackmull, M.-T., Nagel, L., Sesterhenn, F., Muntel, J., Grossbach, J., Stalder, P., Bruderer, R., Reiter, L., Van De Berg, W. D. J., De Souza, N., Beyer, A., & Picotti, P., Nature Structural & Molecular Biology, 29(10), 978–989, 12. Oct 2022, 10.1038/s41594-022-00837-0

[A1] [A5] Distribution of fitness effects of cross-species transformation reveals potential for fast adaptive evolution

Rathmann I., Förster M., Yüksel M., Horst L., Petrungaro G., Bollenbach T., Maier B., ISME J, 12. Oct 2022, 10.1038/s41396-022-01325-5

[A3] [A6] Two modes of evolution shape bacterial strain diversity in the mammalian gut for thousands of generations

Frazão N., Konrad A., Amicone M., Seixas E., Güleresi D., Lässig M. and Gordo I., Nature Communications, 23. Sep 2022, 10.1038/s41467-022-33412-8

[A2] Driven Disordered Systems Approach to Biological Evolution in Changing Environments

Das, S. G., Krug, J., & Mungan, M, Physical Review X, 12(3), 20. Sep 2022, 10.1103/PhysRevX.12.031040

[A1] [A4] Growth-mediated negative feedback shapes quantitative antibiotic response

Angermayr S.A., Pang T.Y., Chevereau G., Mitosch K., Lercher M.J., Bollenbach T., Mol Syst Biol, 20. Sep 2022, 10.15252/msb.202110490

[A2] Unpredictable repeatability in molecular evolution

Das, S. G., & Krug, J., Proceedings of the National Academy of Sciences, 119, 19. Sep 2022, 10.1073/pnas.2209373119

[B1] Pausing methotrexate prevents impairment of Omicron BA.1 and BA.2 neutralisation after COVID-19 booster vaccination

Habermann E., Gieselmann L., Tober-Lau P., Klotsche J., Albach F.N., Ten Hagen A., Zernicke J., Ahmadov E., Arumahandi de Silva A.N., Frommert L.M., Kurth F., Sander L.E., Burmester G.R., Klein F., Biesen R, RMD Open, 12. Sep 2022, 10.1136/rmdopen-2022-002639

[B1] [B3] Design of an optimal combination therapy with broadly neutralizing antibodies to suppress HIV-1

LaMont C., Otwinowski J., Vanshylla K., Gruell H., Klein F., Nourmohammad A., eLife, 19. Jul 2022, 10.7554/eLife.76004

[B1] SARS-CoV-2 Omicron sublineages exhibit distinct antibody escape patterns

Gruell H., Vanshylla K., Korenkov M., Tober-Lau P., Zehner M., Münn F., Janicki H., Augustin M., Schommers P., Sander L.E., Kurth F., Kreer C., Klein F., Cell Host Microbe, 07. Jul 2022, 10.1016/j.chom.2022.07.002

[B1] [B2] Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children

Dewald F., Suárez I., Johnen R., Grossbach J., Moran-Tovar R., Steger G., Joachim A., Rubio G.H., Fries M. , Behr F., Kley J., Lingnau A., Kretschmer A., Gude C., Baeza-Flores G., Laveaga del Valle D., Roblero-Hernandez A., Magana-Cerino J., Hernandez A.T., Ruiz-Quinones J., Schega K., Linne V., Junker L., Wunsch M., Heger E., Knops E., Di Cristanziano V., Meyer M., Hünseler C., Weber L.T., Lüers L.C., Quade G., Wisplinghoff H., Tiemann C., Zotz R., Jomaa H., Pranada A., Herzum I., Cullen P., Schmitz F.J., Philipsen P., Kirchner G., Knabbe C., Hellmich M., Buess M., Wolff A., Kossow A., Niessen J., Jeworutzki S., Schräpler J.-P., Lässig M., Dötsch J., Fätkenheuer D., Kaiser R., Beyer A., Rybniker J., Klein F., Nature Communications, 25. Jun 2022, 10.1038/s41467-022-30664-2

[C2] The impact of genomic variation on protein phosphorylation states and regulatory networks

Grossbach J., Gillet L., Clément-Ziza M., Schmalohr C.L., Schubert O.T., Schütter M., Mawer J.S.P, Barnes C., Bludau I., Weith M., Tessarz P., Graef M., Aebersold R., Beyer A., Molecular Systems Biology, 16. May 2022, 10.15252/msb.202110712

[B1] Cross-Variant Neutralizing Serum Activity after SARS-CoV-2 Breakthrough Infections

Tober-Lau P., Gruell H., Vanshylla K., Koch W.M., Hillus D., Schommers P., Suárez I., Suttorp N., Sander L.E., Klein F., Kurth F., Emerg Infect Dis, 05. May 2022, 10.3201/eid2805.220271

[A2] Stochastic establishment of β-lactam-resistant Escherichia coli mutants reveals conditions for collective resistance

Saebelfeld, M., Das, S. G., Hagenbeek, A., Krug, J., & De Visser, J. A. G. M, Proceedings of the Royal Society B: Biological Sciences, 289(1974), 04. May 2022, 10.1098/rspb.2021.2486

[A1] Intron-mediated induction of phenotypic heterogeneity

Lukačišin, M., Espinosa-Cantú, A. & Bollenbach, T., Nature, 20. Apr 2022, 10.1038/s41586-022-04633-0

[B1] No substantial preexisting B cell immunity against SARS-CoV-2 in healthy adults

Ercanoglu M.S., Gieselmann L., Dähling S., Poopalasingam N., Detmer S., Koch M., Korenkov M., Halwe S., Klüver M., Di Cristanziano V., Janicki H., Schlotz M., Worczinski J., Gathof B., Gruell H., Zehner M., Becker S., Vanshylla K., Kreer C., Klein F., iScience, 03. Mar 2022, 10.1016/j.isci.2022.103951

[A2] Population size mediates the contribution of high-rate and large-benefit mutations to parallel evolution

Schenk M.F., Zwart M.P., Hwang S., Ruelens P., Severing E., Krug J., de Visser J.A.G.M., Nat Ecol Evol, 03. Mar 2022, 10.1038/s41559-022-01669-3

[A5] External stresses affect gonococcal type 4 pilus dynamics

Kraus-Römer, S., Wielert, I., Rathmann, I., Grossbach, J., Maier, B, Frontiers in Microbiology, 25. Feb 2022, 10.3389/fmicb.2022.839711

[B4] Extensive age-dependent loss of antibody diversity in naturally short-lived turquoise killifish

Bradshaw W.J., Poeschla M., Placzek A., Kean S., Valenzano D.R., eLife, 07. Feb 2022, 10.7554/eLife.65117

[B1] mRNA booster immunization elicits potent neutralizing serum activity against the SARS-CoV-2 Omicron variant

Gruell, H., Vanshylla, K., Tober-Lau, P., Hillus, D., Schommers, P., Lehmann, C., Kurth, F., Sander, L.E., Klein, F., Nature Medicine, 19. Jan 2022, 10.1038/s41591-021-01676-0

[B1] [B2] Discovery of ultrapotent broadly neutralizing antibodies from SARS-CoV-2 elite neutralizers

Vanshylla K., Fan C., Wunsch M., Poopalasingam N., Meijers M., Kreer C., Kleipass F., Ruchnewitz D., Ercanoglu M.S., Gruell H., Münn F., Pohl K., Janicki H., Nolden T., Bartl S., Stein S.C., Augustin M., Dewald F., Gieselmann L., Schommers P., Schulz T.F., Sander L.E., Koch M., Łuksza M., Lässig M., Bjorkman P.J., Klein F., Cell Host Microbe, 12. Jan 2022, 10.1016/j.chom.2021.12.010

[B3] Antigenic evolution of human influenza H3N2 neuraminidase is constrained by charge balancing

Wang Y., Lei R., Nourmohammad A., Wu N.C., eLife 2021;10:e72516, 08. Dec 2021, 10.7554/eLife.72516

[B6] [C1] Stochastic clonal dynamics and genetic turnover in exponentially growing populations

Angaji A., Velling C. and Berg J., J. Stat. Mech. 103502, 26. Oct 2021, 10.1088/1742-5468/ac257e

[A4] On the optimality of the enzyme-substrate relationship in bacteria

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[A4] Deep learning allows genome-scale prediction of Michaelis constants from structural features

Kroll A., Engqvist M.K.M., Heckmann D., Lercher M.J., PLOS Biol., 19, 19. Oct 2021, 10.1371/journal.pbio.3001402

[B2] Clinical and Genomic Characterization of SARS CoV-2 infections in mRNA Vaccinated Health Care Personnel in New York City

Robilotti E.V., Whiting K., Lucca A., Poon C., Guest R., McMillen T., Jani K., Solovyov A., Kelson S., Browne K., Freeswick S., Hohl T.M., Korenstein D., Ruchnewitz D., Lässig M., Łuksza M., Greenbaum B., Seshan V.E., Babady N.E., Kamboj M., Clinical Infectious Diseases ciab886, 13. Oct 2021, 10.1093/cid/ciab886

[B8] [C4] Genomic and Transcriptomic Characteristics of Esophageal Adenocarcinoma

Hoppe, S., Jonas, C., Wenzel, M. C., Velazquez Camacho, O., Arolt, C., Zhao, Y., Büttner, R., Quaas, A., Plum, P. S., & Hillmer, A. M, Cancers, 13(17), 26. Aug 2021, 10.3390/cancers13174300

[B2] Superspreaders drive the largest outbreaks of hospital onset COVID-19 infections

Illingworth C.J.R., Hamilton W.L., Warne B., Routledge M., Popay A., Jackson C., Fieldman T., Meredith L.W., Houldcroft C.J., eLife, 10, 24. Aug 2021, 10.7554/eLife.67308

[A2] Antibiotic Breakdown by Susceptible Bacteria Enhances the Establishment of β-Lactam Resistant Mutants

Saebelfeld M., Das S.G., Brink J., Hagenbeek A., Krug J., de Visser J.A.G.M., Frontiers in Microbiology, 12, 19. Aug 2021, 10.3389/fmicb.2021.698970

[B2] Predicting in vivo escape dynamics of HIV-1 from a broadly neutralizing antibody

Meijers M., Vanshylla K., Gruell H., Klein F., Lässig M., PNAS, 118, 27. Jul 2021, 10.1073/pnas.2104651118

[A2] Choice of β-Lactam Resistance Pathway Depends Critically on Initial Antibiotic Concentration

Ruelens P., de Visser J.A.G.M., Antimicrob. Agents Chemother., 65, 16. Jul 2021, 10.1128/AAC.00471-21

[B2] [B5] Antigenic waves of virus–immune coevolution

Marchi J., Lässig M., Walczak A.M., Mora T., PNAS, 118, 06. Jul 2021, 10.1073/pnas.2103398118

[B1] Effective high-throughput isolation of fully human antibodies targeting infectious pathogens

Gieselmann L., Kreer C., Ercanoglu M.S., Lehnen N., Zehner M., Schommers P., Potthoff J., Gruell H., Klein F., Nat Protoc, 25. May 2021, 10.1038/s41596-021-00554-w

[B3] Dynamics of B cell repertoires and emergence of cross-reactive responses in patients with different severities of COVID-19

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[A2] From genotypes to organisms: State-of-the-art and perspectives of a cornerstone in evolutionary dynamics

Manrubia, S., Cuesta, J. A., Aguirre, J., Ahnert, S. E., Altenberg, L., Cano, A. V., Catalán, P., Diaz-Uriarte, R., Elena, S. F., García-Martín, J. A., Hogeweg, P., Khatri, B. S., Krug, J., Louis, A. A., Martin, N. S., Payne, J. L., Tarnowski, M. J., & Weiß, M., Physics of Life Reviews, 38, 55–106, 21. May 2021, 10.1016/j.plrev.2021.03.004

[B1] Kinetics and correlates of the neutralizing antibody response to SARS-CoV-2 infection in humans

Vanshylla K., Di Cristanziano V., Kleipass F., Dewald F., Schommers P., Gieselmann L., Gruell H., Schlotz M., Ercanoglu M.S., Stumpf R., Mayer P., Zehner M., Heger E., Johannis W., Horn C., Suárez I., Jung N., Salomon S., Eberhardt K.A., Gathof B., Fätkenheuer G., Pfeifer N., Eggeling R., Augustin M., Lehmann C., Klein F., Cell Host Microbe, 28. Apr 2021, 10.1016/j.chom.2021.04.015

[B3] Optimal evolutionary decision-making to store immune memory

Schnaack O.H., Nourmohammad A., eLife, 10, 28. Apr 2021, 10.7554/eLife.61346

[B3] [B5] Deep generative selection models of T and B cell receptor repertoires with soNNia

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[B1] Evaluation of a New Spike (S)-Protein-Based Commercial Immunoassay for the Detection of Anti-SARS-CoV-2 IgG

Eberhardt K.A., Dewald F., Heger E., Gieselmann L., Vanshylla K., Wirtz M., Kleipass F., Johannis W., Schommers P., Gruell H., Brensing K.A., Müller R.U., Augustin M., Lehmann C., Koch M., Klein F., Di Cristanziano V., Microorganisms, 31. Mar 2021, 10.3390/microorganisms9040733

[A3] [A5] Adaptive evolution of hybrid bacteria by horizontal gene transfer

Power J.J., Pinheiro F., Pompei S., Kovacova V., Yüksel M., Rathmann I., Förster M., Lässig M., Maier B., PNAS 11, 118(10), 09. Mar 2021, 10.1073/pnas.2007873118

[A3] Metabolic fitness landscapes predict the evolution of antibiotic resistance

Pinheiro, F., Warsi, O., Andersson, D.I., Lässig M., Nat Ecol Evol, 04. Mar 2021, 10.1038/s41559-021-01397-0

[B3] Optimal Evolutionary Control for Artificial Selection on Molecular Phenotypes

Nourmohammad A. & Eksin C., Phys. Rev. X 11, 011044, 04. Mar 2021, 10.1103/PhysRevX.11.011044

[B1] CD34T+ Humanized Mouse Model to Study Mucosal HIV-1 Transmission and Prevention

Vanshylla K., Held K., Eser T.M., Gruell H., Kleipass F., Stumpf R., Jain K., Weiland D., Münch J., Grüttner B., Geldmacher C., Klein F., Vaccines (Basel) 9(3):198, 27. Feb 2021, 10.3390/vaccines9030198

[A2] Clonal Interference and Mutation Bias in Small Bacterial Populations in Droplets

Ruelens P., de Visser J.A.G.M., Genes 2021, 12(2), 04. Feb 2021, 10.3390/genes12020223

[A2] The fitness landscapes of translation

Josupeit M., Krug J., Physica A 569, 125768(2021), 18. Jan 2021, 10.1016/j.physa.2021.125768

[A1] Minimal biophysical model of combined antibiotic action

Kavči B., Tkačik G., Bollenbach T., PLoS Comput Biol, 17, 07. Jan 2021, 10.1371/journal.pcbi.1008529

[B5] Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T-cell memory formation after mild COVID-19 infection

Minervina A.A., Komech E.A., Titov A., Koraichi M.B., Rosati E., Mamedov I.Z., Franke A., Efimov G.A., Chudakov D.M., Mora T., Walczak A.M., Lebedev Y.B., Pogorelyy M.V., eLife 2021, 10:e63502, 05. Jan 2021, 10.7554/eLife.63502

[B7] [C2] Convergent network effects along the axis of gene expression during prostate cancer progression

Charmpi, K., Guo, T., Zhong, Q. et al., Beyer A., Genome Biol, 21 302, 14. Dec 2020, 10.1186/s13059-020-02188-9

[A4] The protein translation machinery is expressed for maximal efficiency in Escherichia coli

Hu X., Dourado H., Schubert P. & Lercher M. J., Nat Commun., 11 5260, 16. Oct 2020, 10.1038/s41467-020-18948-x

[B4] Intra-species differences in population size shape life history and genome evolution

Willemsen D., Cui R., Reichard M., Valenzano D.R., eLife 2020;9:e55794, 01. Sep 2020, 10.7554/eLife.55794

[B3] Information-Geometric Optimization with Natural Selection

Otwinowski J, LaMont C.H., Nourmohammad A., Entropy 2020, 22(9), 31. Aug 2020, 10.3390/e22090967

[A2] Distribution of the number of fitness maxima in Fisher's geometric model

Park S.C., Hwang S. and Krug J., J. Phys. A: Math. Theor., 53(385601), 21. Aug 2020, 10.1088/1751-8121/ab9780

[B1] Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients

Kreer C., Zehner M., Weber T., Ercanoglu M.S., Gieselmann L., Rohde C., Halwe S., Korenkov M., Schommers P., Vanshylla K., Di Cristanziano V., Janicki H., Brinker R., Ashurov A., Krähling V., Kupke A., Cohen-Dvashi H., Koch M, Eckert J.M., Lederer S., Pfeifer N., Wolf T., Vehreschild M.J.G.T., Wendtner C., Diskin R., Gruell H., Becker S., Klein F., Cell, 182, 20. Aug 2020, 10.1016/j.cell.2020.06.044

[B3] [B5] SOS: online probability estimation and generation of T-and B-cell receptors

Isacchini G., Olivares C., Nourmohammad. A, Walczak A.M., Mora T., Bioinformatics, 36(16), 4510–4512, 15. Aug 2020, 10.1093/bioinformatics/btaa574

[A1] Mechanisms of drug interactions between translation-inhibiting antibiotics

Kavčič B., Tkačik G. & Bollenbach T., Nat Commun., 11(4013), 11. Aug 2020, 10.1038/s41467-020-17734-z

[B4] Microbiota–host interactions shape ageing dynamics

Popkes M., Valenzano D.R., Phil. Trans. R. Soc. B 375, 20190596, 10. Aug 2020, 10.1098/rstb.2019.0596

[B2] Eco-evolutionary control of pathogens

Lässig M., Mustonen V., PNAS:201920263, 31. Jul 2020, 10.1073/pnas.1920263117

[B1] Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV

Theobald S.J., Kreer C., Khailaie S., Bonifacius A., Eiz-Vesper B., Figueiredo C., Mach M., Backovic M., Ballmaier M., Koenig J., Olbrich H., Schneider A., Volk V., Danisch S., Gieselmann L., Ercanoglu M.S., Messerle M., Kaisenberg C.V., Witte T., Klawonn F., Meyer-Hermann M., Klein F., Stripecke R., Pathog, 16, 15. Jul 2020, 10.1371/journal.ppat.1008560

[B4] Nothobranchius furzeri (African Turquoise Killifish)

Cui R., Willemsen D., Valenzano D.R., Trends In Genetics, 01. Jul 2020, 10.1016/j.tig.2020.01.012

[A6] Mutation accumulation and horizontal gene transfer in Escherichia coli colonizing the gut of old mice

Barreto H.C., Frazão N., Sousa A., Konrad A., & Gordo I., Communicative & Integrative Biology, 13, 24. Jun 2020, 10.1080/19420889.2020.1783059

[A1] Highly parallel lab evolution reveals that epistasis can curb the evolution of antibiotic resistance

Lukačišinová M., Fernando B., Bollenbach T., Nat Commun 11, 31051, 19. Jun 2020, 10.1038/s41467-020-16932-z

[B3] [B5] Generative models of T-cell receptor sequences

Isacchini G., Sethna Z., Elhanati Y., Nourmohammad A., Walczak A.M., Mora T., Phys. Rev. E 101, 062414, 15. Jun 2020, 10.1103/PhysRevE.101.062414

[A2] Predictable properties of fitness landscapes induced by adaptational tradeoffs

Das S.G., Direito S.O.L., Waclaw B., Allen R.J., Krug J., elife 9, e55155 (2020), 19. May 2020, 10.7554/eLife.55155

[B4] Low mutational load and high mutation rate variation in gut commensal bacteria

Bradshaw W.J., Valenzano D.R., Proc. R. Soc. B.28720200489, 13. May 2020, 10.1098/rspb.2020.0489

[A6] Low mutational load and high mutation rate variation in gut commensal bacteria

Ramiro R.S., Durão P., Bank C., Gordo I., PLoS Biol, 18, 10. May 2020, 10.1371/journal.pbio.3000617

[B7] [C2] Pyruvate kinase variant of fission yeast tunes carbon metabolism, cell regulation, growth and stress resistance

Kamrad S., Grossbach J., Rodríguez‐López M., Mülleder M., Townsend S.J, Cappelletti V., Stojanovski G., Correia‐Melo C., Picotti P., Beyer A., Ralser M., Bähler J., Mol Syst Biol (2020)16:e9270, 01. Apr 2020, 10.15252/msb.20199270

[B1] Structural Basis for a Convergent Immune Response against Ebola Virus

Cohen-Dvashi H., Zehner M., Ehrhardt S., Katz M., Elad N., Klein F., Diskin R., Cell Host Microbe., 27, 11. Mar 2020, 10.1016/j.chom.2020.01.007

[B3] Major antigenic site B of human influenza H3N2 viruses has an evolving local fitness landscape

Wu N. C., Otwinowski J., Thompson A. J., Nycholat C. M. Nourmohammad A and Wilson I. A., Nat Commun 11, 1233, 06. Mar 2020, 10.1038/s41467-020-15102-5

[A4] An analytical theory of balanced cellular growth

Dourado H., and Lercher M. J., Nat Commun 11, 1226, 06. Mar 2020, 10.1038/s41467-020-14751-w

[B5] Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones

Minervina A.A., Pogorelyy M.V, Komech E.A., Karnaukhov V.K., Bacher P. , Rosat E. , Franke A., Chudakov D.M., Mamedov I.Z., Lebedev Y.B., Mora T., Walczak A.M., eLife2020;9:e53704, 21. Feb 2020, 10.7554/eLife.53704

[B3] The size of the immune repertoire of bacteria

Bradde S., Nourmohammad A., Goyal S., and Balasubramanian V., PNAS:201903666, 18. Feb 2020, 10.1073/pnas.1903666117

[B1] Antibody Teamwork against Ebola Virus Disease

Zehner M., Klein F., Immunity., 52, 18. Feb 2020, 10.1016/j.immuni.2020.01.016

[B1] Restriction of HIV-1 Escape by a Highly Broad and Potent Neutralizing Antibody

Schommers P., Gruell H., Abernathy M.E., Tran M.K., Dingens A.S., Gristick H.B., Barnes C.O., Schoofs T., Schlotz M., Vanshylla K., Kreer C., Weiland D., Holtick U., Scheid C., Valter M.M., van Gils M.J., Sanders R.W., Vehreschild J.J., Cornely O.A., Lehmann C., Fätkenheuer G., Seaman M.S., Bloom J.D., Bjorkman P.J., Klein F., Cell, 180, 06. Feb 2020, 10.1016/j.cell.2020.01.010

[B1] openPrimeR for multiplex amplification of highly diverse templates

Kreer C., Döring M., Lehnen N., Ercanoglu M.S., Gieselmann L., Luca D., Jain K., Schommers P., Pfeifer N., Klein F., J Immunol Methods., 480, 25. Jan 2020, 10.1016/j.jim.2020.112752

[B1] [B5] Exploiting B Cell Receptor Analyses to Inform on HIV-1 Vaccination Strategies

Kreer C., Gruell H., Mora T., Walczak A.M., Klein F., Vaccines 8(1) 13, 01. Jan 2020, 10.3390/vaccines8010013

[A1] Emergent Gene Expression Responses to Drug Combinations Predict Higher-Order Drug Interactions

Lukačišin M., Bollenbach T.,Cell Systems 9(5), P423-433.E3, 13. Nov 2019, 10.1016/j.cels.2019.10.004

[B1] Polyclonal and convergent antibody response to Ebola virus vaccine rVSV-ZEBOV

Ehrhardt S.A., Zehner M., Krähling V., Cohen-Dvashi H., Kreer C., Elad N., Gruell H., Ercanoglu M.S., Schommers P., Gieselmann L., Eggeling R., Dahlke C., Wolf T., Pfeifer N., Addo M.M., Diskin R., Becker S., Klein F., Nat Med., 25, 07. Oct 2019, 10.1038/s41591-019-0602-4

[A3] [A6] Horizontal gene transfer overrides mutation in Escherichia coli colonizing the mammalian gut

Frazão N., Sousa A., Lässig M., and Gordo I., PNAS:201906958, 20. Aug 2019, 10.1073/pnas.1906958116

[A2] Recombination and mutational robustness in neutral fitness landscapes

Klug A., Park S.C, Krug J., PLoS Comput Biol, 15, 15. Aug 2019, 10.1371/journal.pcbi.1006884

[B5] Multi-Lineage Evolution in Viral Populations Driven by Host Immune Systems

Nourmohammad A., Otwinowski J., Łuksza M., Mora T., Walczak A.M., Molecular Biology and Evolution, 36, 29. Jul 2019, 10.3390/pathogens8030115

[B1] Modeling the Amplification of Immunoglobulins through Machine Learning on Sequence-Specific Features

Döring M., Kreer C., Lehnen N., Klein F., Pfeifer N., Sci Rep. 9(1):10748, 24. Jul 2019, 10.1038/s41598-019-47173-w

[B3] Fierce Selection and Interference in B-Cell Repertoire Response to Chronic HIV-1

Nourmohammad A., Otwinowski J., Łuksza M., Mora T., M. Walczak A., Molecular Biology and Evolution, msz143, 18. Jun 2019, 10.1093/molbev/msz143

[A3] Survival of the simplest in microbial evolution

Held T., Klemmer D., Lässig M., Nature Communications, 10, 06. Jun 2019, 10.1038/s41467-019-10413-8

[A1] Temporal order and precision of complex stress responses in individual bacteria

Mitosch K., Rieckh G., Bollenbach T., Mol Syst Biol (2019)15:e8470, 14. Feb 2019, 10.15252/msb.20188470

[A4] Each of 3,323 metabolic innovations in the evolution of E. coli arose through the horizontal transfer of a single DNA segment

Pang T. J., Lercher M. J., PNAS, 18. Dec 2018, 10.1073/pnas.1718997115

[A4] Machine learning applied to enzyme turnover numbers reveals protein structural correlates and improves metabolic models

Heckmann D., Lloyd C. J., Mih N., Ha Y., Zielinski D. C., Haiman Z. B., Desouki A. A., Lercher M. J., Palsson B. O., Nature Communications 9: 5252, 07. Dec 2018, 10.1038/s41467-018-07652-6

[A4] Alleles of a gene differ in pleiotropy, often mediated through currency metabolite production, in E. coli and yeast metabolic simulations

Alzoubi D., Desouki A. A., Lercher M. J., Scientific Reports 8: 17252, 22. Nov 2018, 10.1038/s41598-018-35092-1

[B2] Gene expression variability across cells and species shapes innate immunity

Hagai T., Chen X., Miragaia R. J., Rostom R., Gomes T., Kunowska N., Henriksson J., Park J.-E., Proserpio V., Donati G., Bossini-Castillo L., Vieira Braga F. A., Naamati G., Fletcher J., Stephenson E., Vegh P., Trynka G., Kondova I., Dennis M., Haniffa M., Nourmohammad A., Lässig M., Teichmann S. A., Nature, 563, 24. Oct 2018, 10.1038/s41586-018-0657-2

[B8] [C4] Genomic Characterization of TP53–Wild-Type Esophageal Carcinoma1

Quaas A., Heydt C., Gebauer F., Alakus H., Loeser H., Büttner R., Hillmer A., Bruns C., Merkelbach-Bruse S., Zander T., Frommolt P., Transl Oncol., 12, 11. Oct 2018, 10.1016/j.tranon.2018.09.007

[B8] [C4] Impact of TP53 mutation status on systemic treatment outcome in ALK-rearranged non-small-cell lung cancer

Kron A., Alidousty C., Scheffler M., Merkelbach-Bruse S., Seidel D., Riedel R., Ihle M. A., Michels S., Nogova L., Fassunke J., Heydt C., Kron F., Ueckeroth F., Serke M., Krüger S., Grohe C., Koschel D., Benedikter J., Kaminsky B., Schaaf B., Braess J., Sebastian M., Kambartel K. O., Thomas R., Zander T., Schultheis A. M., Büttner R., Wolf J., Ann Oncol., 29, 01. Oct 2018, 10.1093/annonc/mdy333

[A2] Rare beneficial mutations cannot halt Muller's ratchet in spatial populations

Park S.-C., Klatt P., Krug J., EPL, 123, 03. Sep 2018,

[A2] The utility of fitness landscapes and big data for predicting evolution

de Visser, J. A. G. M., Santiago F. E., Fragata I., Matuszewski S., Heredity, 121, 20. Aug 2018, 10.1038/s41437-018-0128-4

[A2] Ecology dictates evolution? About the importance of genetic and ecological constraints in adaptation

de Vos M. G. J., Schoustra S. E., de Visser J. A. G. M., EPL, 122, 17. Jul 2018,

[A2] Unraveling the causes of adaptive benefits of synonymous mutations in TEM-1 β-lactamase

Zwart M. P., Schenk M. F., Hwang S., Koopmanschap B., de Lange N., van de Pol L., Nga T. T. T., Szendro I. G., Krug J., de Visser J. A. G. M., Heredity, 121, 02. Jul 2018, 10.1038/s41437-018-0104-z

[B8] [C4] Genetic instability and recurrent MYC amplification in ALK‐translocated NSCLC: a central role of TP53 mutations

Alidousty C., Baar T., Martelotto L. G., Heydt C., Wagener S., Fassunke J., Duerbaum N., Scheel A. H., Frank S., Holz B., Binot E., Kron A., Merkelbach-Bruse S., Ihle M. A., Wolf J., Büttner R., Schultheis A.M., J Pathol., 246, 09. Jun 2018, 10.1002/path.5110

[B7] [C2] Multi-region proteome analysis quantifies spatial heterogeneity of prostate tissue biomarkers

Guo T., Li L., Zhong Q., Rupp N.J., Charmpi K., Wong C.E., Wagner U., Rueschoff J.H., Jochum W., Fankhauser C.D., Saba K., Poyet C., Wild P.J., Aebersold R., Beyer A., Life Science Alliance, 29. May 2018, 10.26508/lsa.201800042

[B5] Method for identification of condition-associated public antigen receptor sequences

Pogorelyy M.V., Minervina A.A., Chudakov D.M., Mamedov I.Z., Lebedev Y.B., Mora T., Walczak A.M., eLife 2018;7:e33050, 13. May 2018, 10.7554/eLife.33050

[B4] The short-lived African turquoise killifish (Nothobranchius furzeri): a new model system for research on ageing. In Conn's Handbook of Models of Human Aging

Muck J., Kean S., Valenzano D.R., Academic Press, 02. May 2018,

[B4] A Protocol for Laboratory Housing of Turquoise Killifish (Nothobranchius furzeri)

Dodzian J., Kean S., Seidel J., Valenzano D.R., J., Vis. Exp. (134) e57073, 11. Apr 2018, 10.3791/57073

[A2] Universality Classes of Interaction Structures for NK Fitness Landscapes

Hwang S., Schmiegelt B., Ferretti L., Krug J., J Stat Phys, 172, 13. Feb 2018, 10.1007/s10955-018-1979-z

[B5] High-throughput immune repertoire analysis with IGoR

Marcou Q., Mora T., Walczak A.M., Nature Communications Volume 9:561, 08. Feb 2018, 10.1038/s41467-018-02832-w

[B7] [C2] regNet: an R package for network-based propagation of gene expression alterations

Seifert M., Beyer A., Bioinformatics Volume 34 Issue 2:308–311, 15. Jan 2018, 10.1093/bioinformatics/btx544

[A2] Local Fitness Landscapes Predict Yeast Evolutionary Dynamics in Directionally Changing Environments

Gorter F. A., Aarts M. G. M, Zwaan B. J., de Visser J. A. G. M., Genetics, 208, 01. Jan 2018, 10.1534/genetics.117.300519