Project A5
Fitness effects of cross-species gene transfer in bacteria
Berenike Maier, U Cologne | web | email
Project A5 focuses on genome-wide evolution by lateral gene transfer across related Bacillus species. Massively parallel experiments map fitness effects governing the dynamics of gene transfer, including adaptive benefits and fitness barriers generated by functional mismatches between genes from different species in a single organism.
Predictability in Evolution
Collaborative Research Center 1310
Publications
Genome-wide transformation reveals extensive exchange across closely related Bacillus species
Förster M., Rathman I., Yüksel M., Power J., Maier B., Nucleic Acids Reasearch, 16. November 2023, https://doi.org/10.1093/nar/gkad1074
Hennes M., Bender N., Cronenberg T., Welker A., Maier B., PLOS Biol, 18. January 2023, https://doi.org/10.1371/journal.pbio.3001960
Rathmann I., Förster M., Yüksel M., Horst L., Petrungaro G., Bollenbach T., Maier B., ISME J, 12. October 2022, https://www.nature.com/articles/s41396-022-01325-5
Adaptive evolution of hybrid bacteria by horizontal gene transfer
Power J.J., Pinheiro F., Pompei S., Kovacova V., Yüksel M., Rathmann I., Förster M., Lässig M., Maier B., PNAS 11, 118 (10), 9. March 2021, https://doi.org/10.1073/pnas.2007873118
Hepp C., Maier B., BioEssays, 39: 1700099, 12. September 2017, https://doi.org/10.1002/bies.201700099
Kinetics of DNA uptake during transformation provide evidence for a translocation ratchet mechanism
Hepp C., Maier B., PNAS 113(44): 12467, 17. October 2016, https://doi.org/10.1073/pnas.1608110113
Fitness Trade-Offs in Competence Differentiation of Bacillus subtilis
Yüksel M., Power J.J., Ribbe J., Volkmann T., Maier B., Front. Microbiol. 7: 888, 7. June 2016, https://doi.org/10.3389/fmicb.2016.00888