Predictability in Evolution

Collaborative Research Center 1310

Can we predict pathways and outcomes of future evolutionary processes? We work on this question in fast-evolving systems: microbial populations in the laboratory, viruses and immune repertoires, and cancer cell populations. We build high-throughput experiments and models to predict the evolution of drug resistance and immune escape in pathogens, and of the immune answer in their hosts. Applications include the design of antibiotics, of vaccines for influenza and coronavirus, and of therapies for HIV and cancer.

The Collaborative Research Center is funded by Deutsche Forschungsgemeinschaft (DFG) and was established in January 2018.

Science News

Next events

Cologne Evolution Colloquium by Pete Czuppon

29.11.2023        [pdf]

Evolution of drug resistance: mode of action and density regulation

1st Andean School on
Host-Pathogen Dynamics

Bogotá (Colombia), 22.01.2024 - 26.01.2024

Co-organized by CRC 1310 and Universidad de los Andes         
[Further information]