Predictability in Evolution

Collaborative Research Center 1310

Our Mission

Can we predict pathways and outcomes of future evolutionary processes? We work on this question in fast-evolving systems: microbial populations in the laboratory, viruses and immune repertoires, and cancer cell populations. We build high-throughput experiments and models to predict the evolution of drug resistance and immune escape in pathogens, and of the immune answer in their hosts. Applications include the design of antibiotics, of vaccines for influenza and coronavirus, and of therapies for HIV and cancer.

The Collaborative Research Center is funded by Deutsche Forschungsgemeinschaft (DFG) and was established in January 2018.

Science News

Upcoming events

Cologne Evolution Colloquium (online only) Mon, 28.04.2025 | 14:00 Weiwei Zhai Chinese Academy of Sciences Dissecting and targeting a dynamic landscape of tumor evolution in Hepatocellular Carcinoma [pdf]
Cologne Evolution Colloquium Wed, 30.04.2025 | 17:00 Alexandre Persat EPFL Mechanics during Pseudomonas aeruginosa airway infection [pdf]
Joint Colloquium Tue, 13.05.2025 | 16:30 Karen Alim TU München Lesson from smart slime: How active flow networks process information for complex behaviour [pdf]
Bioinformatics Coffee Wed, 14.05.2025 | 14:00 Till Baar Institute of Medical Statistics and Computational Biology, University of Cologne Non-ACTG signal detection in ONT (nanopore) sequencing [pdf]
Cologne Evolution Colloquium Wed, 14.05.2025 | 17:00 Bartek Waclaw Dioscuri Centre for Physics and Chemistry of Bacteria, Warsaw tba [pdf]
Delbrück Lecture Wed, 21.05.2025 | 17:00 Susanna Manrubia Centro Nacional de Biotecnología, Madrid tba [pdf]

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