Project Z3

Evolutionary bioinformatics

Andreas Beyer, U Cologne | web | email

Michael Lässig, U Cologne | web | email

Professional data analysis has become an indispensable tool for research in all areas of quantitative biology, including evolution. In this CRC, we generate and analyse massive high-throughput data, and we develop new computational methods. The central unit of Evolutionary Bioinformatics bundles these efforts. It focuses on common tasks of data analysis, including (1) assistance in the design of complex evolution experiments,
(2) analysis of high-throughput molecular data, (3) time-resolved sequence analysis and tree reconstruction, and (4) implementation of new analysis tools for use in our scientific community.

Predictability in Evolution

Collaborative Research Center 1310

Bioinformatics team

Alina Bazarova

Expertise: Bayesian modelling for Next Generation Sequencing, statistical tests development, sample size calculations,

optimal clinical trials design, agent based simulations, predictive modelling based on machine learning

Phone:     +49 (0)221 470-1050

Email:       a.bazarova@uni-koeln.de

Jan Grossbach

Expertise: RNAseq analysis, Data Independent Acquisition and Data Dependent Acquisition proteomics, integration of omics data,

machine learning, mapping of Quantitative Trait Loci, identification of causal variants

Phone:     +49 (0)221 478-84025

Email:       jan.grossbach@uni-koeln.de

Viera Kovacova

Expertise: Next Generation Sequencing (RNA-seq, DNA-seq), Whole Genome Sequence assembly, phylogenetics,

analysis of Protein-Protein-Interactions

Phone:     +49 (0)221 470-1050

Email:       viera.kovacova@uni-koeln.de

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