Project B4

Co-evolution of gut microbiota and immune cells during ageing in killifish

Dario Riccardo Valenzano, MPI for Biology of Ageing | web | email

We experimentally track the evolution of immune repertoires and microbes in killifish, a model organism of vertebrate ageing. This project develops a predictive approach for the co-evolutionary dynamics of fish B-cell diversity, microbial composition and genetic changes in microbes during the entire host lifespan. Our predictions will include effects of these dynamics on individual ageing.

Predictability in Evolution

Collaborative Research Center 1310