Predictability in Evolution
Collaborative Research Center 1310
Can we predict pathways and outcomes of future evolutionary processes? We work on this question in fast-evolving systems: microbial populations in the laboratory, viruses and immune repertoires, and cancer cell populations. We build high-throughput experiments and models to predict the evolution of drug resistance and immune escape in pathogens, and of the immune answer in their hosts. Applications include the design of antibiotics, of vaccines for influenza and coronavirus, and of therapies for HIV and cancer.
The Collaborative Research Center is funded by Deutsche Forschungsgemeinschaft (DFG) and was established in January 2018.
Delbrück Lecture by Jose Penades
Redefining mobility in bacterial genetics and its impact on infectious disease
Cologne Evolution Colloquium by Ines Mandic-Mulec
Kin discrimination alters bacterial exploitation and horizontal gene transfer
Delbrück Lecture by Terry Hwa
Bacterial growth laws and the origin of dimensional reduction
Delbrück Lecture by Eduardo Rocha
Delbrück Lecture by Daniel Fisher
Delbrück Lecture by Kevin Foster