Predictability in Evolution

Collaborative Research Center 1310

Can we predict pathways and outcomes of future evolutionary processes? We work on this question in fast-evolving systems: microbial populations in the laboratory, viruses and immune repertoires, and cancer cell populations. We build predictive approaches for the evolution of drug resistance and antigenicity in pathogens and of the immune answer in their hosts. Applications include the design of antibiotics, of vaccines for influenza, and of therapies for HIV and cancer.

The Collaborative Research Center is funded by Deutsche Forschungsgemeinschaft (DFG) and was established in January 2018.

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